CBG (cannabigerol) in cannabis


CBG. The primal cannabinoid

Almost everything in the cannabis plant happens because of biosynthesis. What does this mean? Biosynthesis is the combination of the plant compounds in order to form new chemical compounds. In the case of the cannabis plant, the important chemicals are: Geranyl pyrophosphate and Olivetolic acid.

These chemicals are the “bricks” that build the 111 cannabinoids of cannabis. In raw cannabis plants, both geranyl pyrophosphate and olivetolic acid get together in order to produce cannabigerolic acid (CBGA). CBGA combines with enzymes in the plant to produce the other main acidic cannabinoids (THCA, CBDA, CBCA).

So far, research has discovered 111 cannabinoids in cannabis plants. It is true that there aren’t studies enough to fully understand the importance of all them. Therefore, it is a good idea to start understanding the origin of all the cannabinoids: the CBG, cannabigerol. CBG is not psychoactive but its real value is that it is the beginning of all the processes to develop the three most important compounds: THCA (tetrahydrocannabinolic), CBDA (cannabidiolic acid) and CBCA (cannabichromenic acid).

Cannabis plant has enzymes, known as synthase, that decompose CBGA. Once it has been heated or exposed to UV light it becomes CBG. This decomposition is the reason why its levels are so low in most of the cannabis plants.

But besides its importance to form another cannabinoids, it has its own properties. In 2015, some researchers found out that CBG has important neuroprotective effects to treat the Huntington’s disease and also it seems it can slow down the colon cancer.

Each strain can have different amount of this cannabinoid. But those with the highest amount can be very efficient as antidepressant and analgesic.

CBG is also efficient to treat the growth of bacteria and reduces inflammation. It also reduces the propagation of cancer cells and is excellent to increase the bones growth.

CBG also is quite efficient to avoid the uptake of Gamma – Aminobutiryc Acid, which helps to relax. Some studies consider that those varieties with CBG can help to treat skin diseases like psoriasis, and also glaucoma and multiple sclerosis.

Although it is not very efficient, it also has some anti fungal properties.

It seems to be efficient to treat breast cancer when it is used with the terpene known as l-limonene.

CBG can prevent the Methicillin-resistant Staphylococcus aureus.

Unfortunately, CBG is produced during the growing period of the plant and in the flowers. It is available in very small quantities. However, industrial hemp contains more CBG than marijuana plants.

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